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Furthermore, as a hallmark of the aging population, m -Dys could onset chronic inflammation with massive cytokine release and cause multi-organ failure with fatal outcomes in elderly COVID-19 patients 177

Protective effects of quercetin and crocin in the kidneys and liver of obese Sprague-Dawley rats with Type 2 diabetes: Effects of quercetin and crocin on T2DM rats

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Its small size and copper-chelating structure facilitate cellular uptake in laboratory models

Finally, rodents develop neuropathy within weeks, whereas human DN unfolds over years, allowing compensatory mechanisms that animal models simply lack